What is a common sign of jaundice?

Jaundice is primarily characterized by the yellowing of the skin and the whites of the eyes, a result of an excess of bilirubin in the bloodstream. Bilirubin is a yellow pigment that forms during the normal breakdown of red blood cells. When the liver is unable to process bilirubin properly, it accumulates in the body, leading to the distinctive yellow color associated with jaundice.

Recognizing jaundice is important in clinical settings as it can indicate underlying health issues such as liver disease, bile duct obstruction, or hemolytic anemia. The presence of this yellowing is a visual cue that clinicians can use to determine a patient's health status, helping to guide further diagnostic testing and treatment options. As such, the yellowing of the skin is the most direct and representative sign of jaundice.